We all know that an overworked or unhealthy digestive system can make life pretty miserable with too many trips to the bathroom or not enough. In order to keep these functions running smoothly your digestive system needs a proper balance of good vs bad bacteria. Supplementing your diet with probiotics, like goodguts, can help support that balance.
Studies have shown that goodguts probiotic survives to germinate in the intestines and reduce abdominal pain and bloating, reduce post prandial gas and even abdominal pain. In addition to helping you digest food better, goodguts probiotic increased utilisation of consumed nutrients such as protein and minerals.
Bacillus coagulans produce digestive enzymes (Wang & Gu, 2010) that are active under gut conditions (alkaline proteases, etc) and these proteases have been shown to digest proteins more effectively than the endogenous human proteases alone (Minevich et al., 2015).
Bacillus coagulans enhances the health of the cells of the gut lining improving nutrient absorption including minerals, peptides and amino acids by decreasing inflammation and encouraging optimum development of the absorptive area of the villi (Kimmel et al., 2010).
Bacillus coagulans supplementation has been shown to increase population of beneficial bacteria (Nyangale et al., 2014).
In multiple studies goodguts Probiotic supports digestive health when consumed daily.
A Prospective, Randomised, Double-blind, Placebo-controlled, Parallel-group Dual Site Trial To Evaluate The Effects Of A Bacillus Coagulans- based Product On Functional Intestinal Gas Symptoms. BMC Gastroenterology, 2009, 9:85. Douglas S Kalman, Howard I Schartz, Patricia Alvarez, Samantha Feldman, John C Pezzullo and Dianne R Krieger.
This study looked at the effects on gastrointestinal symptoms in adults with post-prandial intestinal gas-related symptoms (abdominal pain, distention, flatulence) but no GI diagnoses to explain the symptoms.
It concluded that a Bacillus coagulans based product was effective in improving the quality of life and reducing GI symptoms in adults with post-prandial intestinal gas-related symptoms (abdominal pain, distention, flatulence) but no GI diagnoses.
Survival and metabolic activity of the GanedenBC30 strain of Bacillus coagulans in a dynamic in vitro model of the stomach and small intestine. Beneficial microbes, published online October 06, 2009. A. Maathuis, D. Keller, S. Farmer.
The results show the potential of the probiotic to aid in protein digestion and in the digestion of lactose and fructose. The importance of the findings: the potential of the probiotic to aid in the digestion of lactose and fructose could be used to prevent occurrence of intestinal symptoms in individuals sensitive to these carbohydrates.
Bacillus Coagulans Significantly Improved Abdominal Pain And Bloating In Patients With IBS. Postgraduate Medicine, 2009: 121(2): 119-124. Larysa Hun.
Symptoms of IBS can have a profound impact on emotional health and quality of life, and current treatments are sometimes unsatisfactory for patients. Probiotics, which can normalise gastrointestinal microflora, may alleviate symptoms of IBS.
This study showed statistically significant improvement for abdominal pain and bloating. Results suggest that the patented Bacillus coagulans may be a safe and effective option for the relief of abdominal pain and bloating for patients with IBS.
Impact of Bacillus Coagulans on population dynamics of the human gut microbes in a continuous culture Fermentation system. International Journal of Probiotics and Prebiotics, 2011, 6(1): 65-72 Harue Honda, Lesley Hoyles, Glenn R. Gibson, Sean Farmer, David Keller and Anne L. McCartney.
A validated large intestinal model (ascending colon) that demonstrated that the patented Bacillus coagulans germinates and populates the colon.
Effects Of A Proprietary Bacillus Coagulans Preparation On Symptoms OF Diarrhea-Predominant Irritable Bowel Syndrome. Methods Find Exp Coin Pharmacoil 2009; 31(10): 655-659. B.J. Dolin.
Symptoms of IBS have a profound impact on quality of life for many patients and current treatments are sometimes unsatisfactory. This controlled trial showed that Bacillus coagulans supports digestive health and is effective by reducing the number of bowel movements per day in patients with IBS-D.
Bacillus Coagulans Modulates Faecalibacterium prausnitzii in Older Men and Women. The Journal of Nutrition May 2015 Edna P Nyangale, Sean Farmer, Howard A. Cash, David Keller, David Chernoff, and Glenn R Gibson.
Advancing age is linked to a decrease in beneficial bacteria and reduced aspects of innate immune function. Daily consumption of the patented bacillus coagulans by adults aged 65-80 can increase beneficial groups of bacteria in the human gut and potentially increase production of anti-inflammatory cytokines. This study shows the potential benefits of a probiotic to improve dysbiosis via modulation of the microbiota in older persons.
Effects of probiotics on the fecal microbiota of elderly volunteers after dietary supplementation of the patented Bacillus coagulans. Anaerobe Volume 30 201 Edna P. Nyangale et al.,
In advancing age, gut populations of beneficial microbes show a marked decline. This contributes to an environment less capable of maintaining homeostasis. This study investigated the possible synergistic effects of probiotic supplementation in modulating the gut macrobiotic enabling prebiotic therapy to elderly persons.
In a validated large intestinal model, it was demonstrated that there is an increased effect of elevated populations of beneficial genres of bacteria as well as organic acid production when consuming prebiotics along with the patented Bacillus coagulans versus prebiotics alone.
RESEARCH ON OUR CULTURE EFFECT ON IMMUNE HEALTH
A large majority of the body’s immune system is located within the intestines. When goodguts probiotic is consumed daily, it creates a healthier intestinal environment, supporting Immune function.
Studies have shown that when the body is challenged (by colds and the flu for example) goodguts probiotic helps up regulate the protective cytokines which help fight the challenge. When the body is challenged by over active cytokines (inflammation related to arthritis, for example) it helps down regulate these cytokines.
A Controlled Clinical Trial to Evaluate The Effects of Bacillus Coagulans On Immunological Markers. Methods and Findings in Experimental and Clinical Pharmacology 2010, 32(23): 129-132. M. Kimmel, D. Keller, S. Farmer, D.E. Warrino.
A controlled trial that showed that Bacillus coagulans supports immune health by increasing immune response to multiple viral challenges and that a regimen of 500 million cfu of Bacillus coagulans per day may be a safe and effective option for enhancing the immunological response to common viral respiratory tract infections.
Bacillus Coagulans Modulates Faecalibacterium prausnitzii in Older Men and Women. The Journal of Nutrition May 2015. Edna P Nyangale, Sean Farmer, Howard A. Cash, David Keller, David Chernoff, and Glenn R Gibson.
Advancing age is linked to a decrease in beneficial bacteria and reduced aspects of innate immune function. Daily consumption of the patented Bacillus coagulans by adults aged 65-80 can increase beneficial groups of bacteria in the human gut and potentially increase production of anti-inflammatory cytokines. This study shows the potential benefits of a probiotic to improve dysbiosis via modulation of the microbiota in older persons.
Bacillus Coagulans Cell Wall and Metabolites: Anti-inflammatory and Immune Modulating Effects In Vitro. BMC Immunology 2010, 11:1. Gitte S Jensen, Kathleen F Benson, Steve G Carter, John R Endres.
This study was performed to evaluate anti-inflammatory and immune modulating properties of the patented bacillus coagulans.. The data suggests that consumption of Bacillus coagulans may introduce both cell wall components and metabolites that modulate inflammatory processes in the gut. Both the cell wall and the supernatant possess strong immune modulating properties in vitro. The anti-inflammatory effects are of interest to possible treatment of inflammatory bowel diseases as well as in support of a healthy immune system.
Probiotic metabolites from Bacillus Coagulans supports maturation of antigen-presenting cells in vitro. World Journal of Gastroenterology, 2012, 18(16): 1875-1883. Kathleen F Benson, Kimberlee A Redman, Steve G Carter, David Keller, Sean Farmer, John R Endres and Gitte S Jensen.
This research showed that a primary mechanism of action of the patented bacillus coagulans metabolites involves support of more mature phenotypes of antigen presenting cells, important for immunological decision-making.
A patented strain of Bacillus Coagulans Increased Immune Response to Viral Challenge. Postgraduate Medicine, 2009; 121(23): 114-118. Mira Baron.
Viral respiratory tract infection is the most common illness among humans. Probiotics have been known to enhance the immune system and may represent therapeutic advancement for treating viral respiratory tract infections. This study showed that Bacillus coagulans may be a safe and effective therapeutic option for enhancing T-cell response to certain viral respiratory tract infections.
RESEARCH ON OUR CULTURE EFFECT ON EXERCISE & MUSCLE RECOVERY
Protein supplementation improves recovery and training adaptions, resulting in an increase in lean body mass with subsequent greater gains in strength and power (Campbell et al, 2007)
Microbiota composition and diversity positively correlates with protein intake and exercise and is linked to a more favourable inflammatory and metabolic profile.
While moderate exercise intensity reduces infection risk, high intensity exercise actually increases infection risk. Immune suppression in athletes worsens by psychological stress, environmental extremes, exposure to large crowds, or increased exposure to pathogens due to elevated breathing during exercise (Neiman, 1997).
Probiotics have been reported to reduce the number, severity, and duration of upper respiratory infections and GI distress in athletes (Gleeson et al., 2011; Salarkia et al., 2013; Haywood et al., 2014; Cox et al., 2010).Probiotic Bacillus coagulans GBI-30, 6086 reduces exercise-induced muscle damage and increases recovery. (PeerJ, July 2016. Ralf Jäger, Kevin A. Shields, Ryan P. Lowery, Eduardo O. De Souza, Jeremy M. Partl, Chase Hollmer, Marin Purpura and Jacob M. Wilson
This research examined the effect of administration of protein and Bacillis coagulans probiotic on muscle damage, and performance following a damaging exercise bout. The results provide evidence that Bacillus Coagulans supplementation in combination with protein tended to reduce muscle damage, improves recovery time, and prevented the decline in peak power maintaining physical performance subsequent to damaging exercises – as measured by a reduction in muscle swelling, reduction in blood creatine kinase levels, decrease in soreness, increase in perceived recovery, increase in power and an increase in amino acid levels.
Combined effect of Bacillus coagulans GBI-30, 6086 and HMB supplementation on muscle integrity and cytokine response during intense military training. (Yftach Gepner, Jay R. Hoffman, Elad Shemesh, Jeffrey R. Stout, David D. Church, Alyssa N. Varanoske, Hila Zelicha, Ilan Shelef, Yacov Chen, Hagai Frankel, and Ishay Ostfeld . 1 JUL 2017)
The purpose of this study was to compare the coadministration of the probiotic Bacillus coagulans GBI-30, 6086 (BC30) with β-hydroxy-β-methylbutyrate (HMB) calcium (CaHMB) to CaHMB alone on inflammatory response and muscle integrity during 40 days of intense military training. Results provide further evidence that the combination of the probiotic BC30 with CaHMB may be more beneficial in maintaining muscle integrity during intense military training.
RESEARCH ON OUR CULTURE EFFECT ON PLANT PROTEIN ABSORPTION.
Bacillus coagulans BGI-30, 6086 increases plant protein digestion in a dynamic, computer-controlled in vitro model of the small intestine. D. Keller et al. Beneficial microbes 2017.
This research assessed the potential of Bacillus coagulans to aid in protein digestion of plant proteins – pea, soy and rice.
Bacillus coagulans increased protein digestion and uptake in the upper GI tract, which reduced the amount of protein that would be delivered to the colon, which could be fermented into toxic metabolites by the gut microbiota. The enhanced proteins digestion by the patented bacillus coagulans showed a dual benefit: enhanced amino acid bioavailability from plant proteins in the upper GI tract, and a healthier environment in the colon.
RESEARCH ON OUR CULTURE EFFECT ON RHEUMATOID ARTHRITIS
Lactic acid producing bacteria (such as Bacillus coagulans) probiotics demonstrate immunomodulating and anti inflammatory effects and the ability to lessen the symptoms of arthritis in humans.
Bacillus Coagulans: A Viable Adjunct Therapy For Relieving Symptoms Of Rheumatoid Arthritis According To A Randomised, Controlled Trial. BMC Complementary and Alternative Medicine 2010, 10:1. David R Mandel, Katy Eichas, Judith Holmes.
The results of this pilot study suggest that adjunctive treatment with Bacillus coagulans probiotic appeared to be safe and effective for patients suffering from Rheumatoid Arthritis. The trial results showed that Bacillus coagulans improved pain symptoms and increased mobility in subjects with Rheumatoid Arthritis.
RESEARCH ON THE SAFETY OF OUR CULTURE
Safety assessment of a proprietary preparation of a novel probiotic, Bacillus Coagulans, as a food ingredient. Food and chemical toxicology, 2009 J.R. Endresa, A. Clewella, K.A. Jadea, T. Farberb, J. Hauswirthe, A.G. Schaussa
One-year chronic oral toxicity with combined reproduction toxicity study of a novel probiotic, Bacillus Coagulans, as a food ingredient. Food and chemical toxicology articles in press. J.R. Endresa, I. Qureshia, T. Farberb, J. Hauswirthe, G. Hirkad, I Pasicsd, A.G. Schaussa.